Fertility and Sterility, 44(6), 760-765
To determine whether changes in circulating levels of neuropeptides are associated with symptoms of premenstrual syndrome (PMS), 20 women with the diagnosis of PMS and 20 asymptomatic subjects were studied. The premenstrual beta-endorphin levels were significantly lower in PMS patients (P = 0.0001). The decrease in beta-endorphin levels during the luteal phase, compared with the follicular phase, in PMS patients was also significant (P = 0.0002). Neurotensin, human pancreatic peptide, vasoactive intestinal polypeptide, gastrin, and bombesin-like immunoreactivity levels did not reveal significant changes between days 7 and 25 in patients with PMS.
Chuong, C. J., Kao, P. C., Bergstralh, E. J., Go, V. L., & Coulam, C. B. (1985). Neuropeptide levels in premenstrual syndrome. *Fertility and sterility*, *44*(6), 760-765. https://doi.org/10.1016/s0015-0282(16)49034-5
Chuong CJ, Kao PC, Bergstralh EJ, Go VL, Coulam CB. Neuropeptide levels in premenstrual syndrome. Fertil Steril. 1985;44(6):760-765. doi:10.1016/s0015-0282(16)49034-5
Chuong, C. J., et al. "Neuropeptide levels in premenstrual syndrome." *Fertility and sterility*, vol. 44, no. 6, 1985, pp. 760-765.
Adolescent, Adult, Bombesin/blood, Endorphins/blood, Female, Gastrins/blood, Humans, Menstrual Cycle, Middle Aged, Nerve Tissue Proteins/blood, Neurotensin/blood, Pancreatic Polypeptide/blood, Premenstrual Syndrome/blood, Vasoactive Intestinal Peptide/blood, beta-Endorphin, Endorphins, Gastrins, Nerve Tissue Proteins, Vasoactive Intestinal Peptide, Neurotensin, Pancreatic Polypeptide, beta-Endorphin, Bombesin,